CONFERENCE PROCEEDING
Dietary patterns to slow cognitive decline
1
University of Nicosia, Nicosia, Cyprus
Publication date: 2022-05-27
Public Health Toxicol 2022;2(Supplement Supplement 1):A23
ABSTRACT
Background:
As the population is ageing, the prevalence of dementia is expected to increase with huge burdens on individuals and society. Nutrition is a modifiable risk factor with both direct and indirect effects on the risk of dementia1,2.
Methods:
A review of the evidence on dietary patterns and interventions associated with a reduced cognitive decline will be presented.
Results:
Higher adherence to dietary patterns such as the Mediterranean and MIND diets have been associated with a reduced cognitive decline in various populations3-5. Emerging evidence suggests that multicomponent interventions such as that used in the FINGER study6 result in improvement of cognitive outcomes in older individuals. A number of mechanisms linking nutrition and cognitive outcomes such as reduction in inflammation and oxidation, changes in gut microbiota profile and reduction in comorbidities have been suggested7,8. Dietary recommendations aiming to reduce cognitive decline of the ageing brain are available9.
Conclusions:
Healthy dietary patterns provide a valuable means to slow cognitive decline especially within a multidisciplinary approach. Further research to better understand the timing, duration and content of interventions is necessary.
As the population is ageing, the prevalence of dementia is expected to increase with huge burdens on individuals and society. Nutrition is a modifiable risk factor with both direct and indirect effects on the risk of dementia1,2.
Methods:
A review of the evidence on dietary patterns and interventions associated with a reduced cognitive decline will be presented.
Results:
Higher adherence to dietary patterns such as the Mediterranean and MIND diets have been associated with a reduced cognitive decline in various populations3-5. Emerging evidence suggests that multicomponent interventions such as that used in the FINGER study6 result in improvement of cognitive outcomes in older individuals. A number of mechanisms linking nutrition and cognitive outcomes such as reduction in inflammation and oxidation, changes in gut microbiota profile and reduction in comorbidities have been suggested7,8. Dietary recommendations aiming to reduce cognitive decline of the ageing brain are available9.
Conclusions:
Healthy dietary patterns provide a valuable means to slow cognitive decline especially within a multidisciplinary approach. Further research to better understand the timing, duration and content of interventions is necessary.
REFERENCES (9)
1.
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Livingston G, Sommerlad A, Orgeta V, et al. Dementia prevention, intervention, and care. Lancet. 2017;390(10113):2673-2734. doi:10.1016/S0140-6736(17)31363-6
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Wu J, Song X, Chen GC, et al. Dietary pattern in midlife and cognitive impairment in late life: a prospective study in Chinese adults. Am J Clin Nutr. 2019;110(4):912-920. doi:10.1093/ajcn/nqz150
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Shannon OM, Stephan BCM, Granic A, et al. Mediterranean diet adherence and cognitive function in older UK adults: the European Prospective Investigation into Cancer and Nutrition-Norfolk (EPIC-Norfolk) Study. Am J Clin Nutr. 2019;110(4):938-948. doi:10.1093/ajcn/nqz114
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McEvoy CT, Hoang T, Sidney S, et al. Dietary patterns during adulthood and cognitive performance in midlife: The CARDIA study. Neurology. 2019;92(14):e1589-e1599. doi:10.1212/WNL.0000000000007243
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McMaster M, Kim S, Clare L, et al. Lifestyle Risk Factors and Cognitive Outcomes from the Multidomain Dementia Risk Reduction Randomized Controlled Trial, Body Brain Life for Cognitive Decline (BBL-CD). J Am Geriatr Soc. 2020;68(11):2629-2637. doi:10.1111/jgs.16762
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Petersson SD, Philippou E. Mediterranean Diet, Cognitive Function, and Dementia: A Systematic Review of the Evidence. Adv Nutr. 2016;7(5):889-904. doi:10.3945/an.116.012138
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Chu CQ, Yu LL, Qi GY, et al. Can dietary patterns prevent cognitive impairment and reduce Alzheimer's disease risk: Exploring the underlying mechanisms of effects. Neurosci Biobehav Rev. 2022;135:104556. doi:10.1016/j.neubiorev.2022.104556
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Philippou E, Polak R, Michunovich A, et al. Food for Thought: Basic Nutrition Recommendations for the Mature Brain. Arch Phys Med Rehabil. 2019;100(8):1581-1583. doi:10.1016/j.apmr.2019.01.006
| ISSN: | 2732-8929 |
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