Introduction:
Background: Τhe genetic cause of obesity has aroused the interest of researchers, whom the science of Nutritional Genetics and Nutritional Genomics is helping to develop new methods for managing obesity¹. This arises from various genome analysis studies, in which results show that gene polymorphisms are associated with the increased body mass index and obesity².

Purpose:
Ιnvestigate how the dietary behavior and lifestyle of the sample are related to the increased of BMI and possible predisposition to obesity, αs well as the knowledge about the interaction of genome and diet in a sample of the Greek population.

Methodology:
300 questionnaires from a random sample were completed electronically via network community. The questionnaire consisted of 28 questions, of which the first part was related to demographic data, the second part was related on eating behavior and lifestyle and the third part was about the knowledge of the sample on gene - diet interaction. Statistical frequency and x2 independence analysis and graphing were performed with Microsoft Excel and SPPS 21 software.

Results:
The 71.3% consider diet to be the main cause of obesity, while only 2% consider the genetics. From the analysis of the lifestyle and nutritional behavior of the sample, it emerged that obese people adopt habits that exacerbate weight gain. Also, the majority of samples did not have knowledge about gene-diet interaction but they would be interested to know about it. However, they would change their eating habits and receive personalized dietary advice if they knew they had a genetic predisposition to obesity.

Discussion - Conclusions:
Therefore, it is necessary to inform people about issues related to the predisposition of obesity and the correlation of genes and their interaction with the obese environment in the appearance of obesity. Finally, the provision of personalized knowledge could be a useful tool for providing targeted nutritional recommendations.