CONFERENCE PROCEEDING
Studying the migration of phthalates and other volatile compounds from disposable tableware used for food preparation and consumption
1
National Scientific Center for “Toxicological and Biological Safety of Medical Devices" Limited, Moscow, Russia
2
Department of Chemistry, Lomonosov Moscow State University, Moscow, Russia
Publication date: 2024-11-26
Public Health Toxicol 2024;4(Supplement Supplement 2):A13
KEYWORDS
ABSTRACT
Introduction:
Phthalates are a group of synthetic organic compounds widely used in industry. These compounds are potentially harmful to human health as they can disrupt the endocrine system. This property of phthalates has led to the adoption of regulations regarding the types and levels of acceptable phthalate content in plastic toys, water containers, textiles and food products, etc. Phthalates can potentially migrate from plastic products into the environment.
Methods:
Both qualitative and quantitative assessment methods have been developed to study the migration of phthalates from disposable plastic tableware. Qualitative assessment is carried out using GC-MS (gas chromatography-mass spectrometry) with preliminary thermal desorption, while quantitative assessment is carried out using HPLC-UV (high performance liquid chromatography with ultraviolet detection). To determine the quantitative content of dibutyl phthalate and bis(2-ethylhexyl) phthalate released, a calibration curve was constructed based on concentrations ranging from 0.1 to 4.0 mg/L of the target compounds. Extraction from disposable plastic tableware was carried out with constant stirring at 37 ± 0.5℃ for 24 h using the following media: water, a mixture of water and ethanol at a ratio of 1:10, and a mixture of water and ethanol at a ratio of 4:1.
Results:
The method has proven itself satisfactorily in the identification and quantification of dibutyl phthalate and bis (2-ethylhexyl) phthalate in target matrices. The linearity of the calibration graphs was highly acceptable, which was confirmed by a high correlation coefficient (r≥0.999). The concentration ranges for the samples were as follows: 0.1–4 mg/L for the target compounds. The quantitative determination of dibutyl phthalate and bis (2-ethylhexyl) phthalate was calculated using the least squares method. The developed methods of GC-MS, with preliminary thermal desorption and HPLC-UV, have made it possible to evaluate the qualitative and quantitative composition of extracts from plastic disposable tableware.
Conclusions:
Based on the results obtained, we can conclude about the migration of dibutyl phthalate and bis (2-ethylhexyl) phthalate from plastic disposable tableware under the given conditions.
Phthalates are a group of synthetic organic compounds widely used in industry. These compounds are potentially harmful to human health as they can disrupt the endocrine system. This property of phthalates has led to the adoption of regulations regarding the types and levels of acceptable phthalate content in plastic toys, water containers, textiles and food products, etc. Phthalates can potentially migrate from plastic products into the environment.
Methods:
Both qualitative and quantitative assessment methods have been developed to study the migration of phthalates from disposable plastic tableware. Qualitative assessment is carried out using GC-MS (gas chromatography-mass spectrometry) with preliminary thermal desorption, while quantitative assessment is carried out using HPLC-UV (high performance liquid chromatography with ultraviolet detection). To determine the quantitative content of dibutyl phthalate and bis(2-ethylhexyl) phthalate released, a calibration curve was constructed based on concentrations ranging from 0.1 to 4.0 mg/L of the target compounds. Extraction from disposable plastic tableware was carried out with constant stirring at 37 ± 0.5℃ for 24 h using the following media: water, a mixture of water and ethanol at a ratio of 1:10, and a mixture of water and ethanol at a ratio of 4:1.
Results:
The method has proven itself satisfactorily in the identification and quantification of dibutyl phthalate and bis (2-ethylhexyl) phthalate in target matrices. The linearity of the calibration graphs was highly acceptable, which was confirmed by a high correlation coefficient (r≥0.999). The concentration ranges for the samples were as follows: 0.1–4 mg/L for the target compounds. The quantitative determination of dibutyl phthalate and bis (2-ethylhexyl) phthalate was calculated using the least squares method. The developed methods of GC-MS, with preliminary thermal desorption and HPLC-UV, have made it possible to evaluate the qualitative and quantitative composition of extracts from plastic disposable tableware.
Conclusions:
Based on the results obtained, we can conclude about the migration of dibutyl phthalate and bis (2-ethylhexyl) phthalate from plastic disposable tableware under the given conditions.
ACKNOWLEDGEMENTS
The study was carried out using the equipment of the Central Collective Use Center of Moscow State University Technologies for Obtaining New Nanostructured Materials and Their Comprehensive Study, acquired by Moscow State University under the program for updating the instrumentation base within the framework of the national project ‘Science’ and the Development Program of Moscow State University.
CONFLICTS OF INTEREST
The authors declare that they have no conflict of interest in the publication of this article. The authors have no conflicts of interest to report in this work. Abstract was not submitted elsewhere and was first published here.
FUNDING
This research received no external funding from any funding agency in the public, commercial, or not-for-profit sectors.
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| ISSN: | 2732-8929 |
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